Improved Method to Predict Salmonella Heat Inactivation

Summary: A new modelling approach to estimate Salmonella inactivation in low-moisture foods under non-isothermal elevated-heat conditions involves tracking temperature changes in real-time and applying sequential kinetic modelling.

Source links: Journal of Food Protection 

A word cloud focused on food safety, with the acronym HACCP (Hazard Analysis and Critical Control Points) appearing in large, bold black letters in the center. The background consists of various terms in different sizes, colors (red, blue, and black), and orientations. Frequent words include "Listeria," "E. Coli," "Food Poisoning," "Recall," "Salmonella," and "Food Borne Illness." Most of the background text is slightly blurred, making the central "HACCP" stand out as the primary focus.

Estimating Salmonella Inactivation in Low Moisture Foods

(Image Credit: iStock/zimmytws)

Why This Matters:

  • Risk in low-moisture foods: Flaxseed and other low-moisture foods (LMFs) are challenging to decontaminate and Salmonella is notoriously heat resistant in such matrices. Traditional thermal validation often assumes constant temperature, which can misestimate lethality.
  • Real-world process relevance: Industrial thermal processes seldom maintain perfect isothermal conditions. This modeling strategy provides better-aligned validation data for actual production scenarios, improving both safety and efficiency.
  • Regulatory and preventive controls: More accurate inactivation parameters support robust HACCP/FSMA preventive control plans, helping processors demonstrate required log-reductions under process deviations.
  • Generalizable tool: While applied to flaxseed, this framework could be extended to other LMFs (nuts, spices, powders), enabling broader improvements in food safety validation.

Key Findings: 

Faliarizao et al. (2025) have elaborated a novel modeling approach to estimate Salmonella inactivation parameters under non-isothermal (dynamic) elevated-heat conditions.1 By tracking temperature changes in real-time during heating and applying sequential kinetic modeling (e.g., Weibull), they derive inactivation parameters that better reflect real-process conditions than traditional isothermal models. Their method quantifies D-values and z-values adapted to fluctuating temperature profiles, offering a more realistic basis for food safety validation in low-moisture food (LMF) processing.

 

Bigger Picture:

This study represents a meaningful step forward in predictive microbiology for food safety, particularly for low-moisture foods. By acknowledging and modeling non-isothermal heating, Faliarizao et al. offer a more accurate, process-relevant way to estimate pathogen reduction.

Key considerations for food safety and quality assurance teams: ·  

  • Incorporating their method could reduce over-engineering of thermal processes, saving energy or reducing product degradation while still achieving the required log reductions.
  • It strengthens the scientific defensibility of HACCP or preventive control validations by aligning thermal process parameters with real-world behavior.
  • As this modelling approach is adapted to other LMFs, it could help raise the bar for process safety validation across the food industry.

References:

  1. Faliarizao et al. (2025). A New Approach to Estimate Salmonella Inactivation Parameters During Dynamic Elevated Heat Treatment: A Case Study with Flaxseed. Journal of Food Protection, 100666.

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